Fenbendazole for humans is a medication used to treat parasites and worms (roundworms, hookworms, whipworms, and certain tapeworms) in animals. It debuted in scientific studies as an anti-cancer drug some years ago and was branded under the names Safe-Guard or Panacur, but has since come into prominence due to a story of a man curing his own stage four small cell lung cancer by taking this “worm-eating” drug alone.
Fenbendazole has polymerization inhibitory effects on tubulin, which are polymers that form microtubules, which give shape and structure to cells. Microtubules also provide a platform for the action of cytotoxic anti-cancer drugs such as vinca alkaloids and taxanes. Fenbendazole may be able to enhance the effectiveness of these drugs by targeting microtubules.
Specifically, fenbendazole induces G2/M arrest and apoptosis in 5-FU-sensitive SNU-C5 and SNU-C5/5-FUR CRC cells. It also causes necroptosis in both these cell lines through glutathione peroxidase-mediated ferroptosis. It does so by activating p53, decreasing mutant p53 expression, and increasing the activity of necroptosis-related proteins such as RIP1, RIP3, and phosphor-mixed lineage kinase domain-like protein (pMLKL).
While fenbendazole for humans is well studied in animal models, it has not yet been proven to be safe for human consumption for prolonged periods of time. However, many individuals are using fenbendazole on their own in conjunction with DCA and other anti-cancer therapies. Some are reporting great success, while others are experiencing side effects. In order to determine if fenbendazole for humans will work for you, speak with a doctor about your options. fenbendazole for humans